Tuesday, June 16, 2015

Day 63

210 mg yesterday

Paper and pen logged night time doses:


Monday, June 15, 2015

Slight change to trial plan

given that adequate rest is an important element of the Swank diet and lifestyle, I sm going to try to cut down on dose logging at night.

Plan is to take enough at bedtime to get to 200 mg for day and take 20 - 30 mg at wake up with few - no midnight doses.

Day 62

200 mg yesterday

Saturday, June 13, 2015

Thursday, June 4, 2015

The Plan (reposted at day 52)

Trial plan:

·         Using 10,000 mcg (microgram) biotin from Natrol via Amazon.com
See Which biotin - now using Natures bounty exclusively.  It is d-biotin, calcium free, $9 per 6 day supply (120 x 10 mg is 6 days per my protocol).
·         Taking biotin with Swiss chard (just a pinch) or peanuts sunflower seeds (just a few)
·         1 unit once per waking hour
o   Or 2 units per 2 hours if necessary, always with biotin containing food
·         1-2 units if I wake up in the middle of the night for anything
·         Target 15 – 20 units daily (19 - 21 units daily so far)
·         Maintain this plan for at least 12 months
·         Keep a log of actuals – recognizing that this is a difficult plan to adhere to


·         Patent based on 100 mg – 600 mg daily was well tolerated, therefor 200 mg should be safe
o   Biotin is water soluble and doesn’t build up in the body – excess will be excreted
o   Results were seen in case studies as low as 100 mg daily, most patients were given 300 mg
o   150-200 at the suggested interval most likely as effective as 300 in 3 daily doses
·         Half-life of biotin is 2 hours – that is why the frequent distributed dosing schedule
·         Food containing biotin most likely also contain elements that aid in the body’s absorption of biotin
o   Peanuts, swiss chard, egg yolks (but egg yolks contain saturated fat which is contra-indicated for MS)
·         Patients took 2 – 12 months to see results.  Will commit to this study for 12 months
o   Patients had very advanced progressive MS and still saw improvements – very exciting research geared towards recovering lost function


·         All indications are that this is safe.  Still – we are talking about hundreds or thousands of times the daily recommendation for Biotin
·         I’ve estimated cost to be around $45 per month.
o   There is a cheaper but less convenient and safe way to do this
o   Bulk pharmaceutical grade biotin is available for $166 / kg which would last more than a year at this dosing plan

o   This is less safe and less accurate and only saves $384 over the course of a year.  I don’t recommend it.

Tuesday, June 2, 2015

Day 49

210 mg yesterday.

Yesterday was very uneven with lots of missed doses and double doses.  I was extremely busy from early AM to late PM.

Part of the reason for keeping this log is recognition that 10 mg 20 x per day is an ambitious plan.  I want to be able to look back and see the "actual" - not just the idealistic version of what I think I did.